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Reversin 121
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Reversin 121图片
CAS NO:174630-04-7
规格:98%
分子量:641.8
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance.
CAS:174630-04-7
分子式:C34H47N3O9
分子量:641.8
纯度:98%
存储:Store at -20°C

Background:

Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. It binds to the P-glycoprotein multidrug transporter (MDR1) with a Kd value of 77 nM. Reversin 121 modulates P-glycoprotein ATPase activity in Sf9 insect cell membranes expressing human MDR1, plasma membrane vesicles from multidrug-resistant cells, and reconstituted proteoliposomes as well as in a variety of MDR1-expressing intact tumor cells.