| CAS NO: | 1268244-85-4 |
| 规格: | 98% |
| 分子量: | 554.85 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 2mg | 电议 |
Background:
PX20606 trans racemate is a FXR agonist with EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively.
[1]. Kinzel O, et al. Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3746-53.
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