Salicyl-AMS是可以抑制分支杆菌生长素生物合成的抑制剂,且在体外缺铁定的条件下能抑制结核分枝杆菌的生长。
CAS：863238-55-5
分子式：C17H18N6O8S
分子量：466.43
纯度：98%
存储：Store at -20°C

Background:

Salicyl-AMS is a mycobactin biosynthesis inhibitor which can also inhibit M. tuberculosis growth in vitro under iron-limited conditions.

[1]. Lun S, et al. Pharmacokinetic and in vivo efficacy studies of the mycobactin biosynthesis inhibitor salicyl-AMS in mice. Antimicrob Agents Chemother. 2013 Oct;57(10):5138-40. [2]. Ferreras JA, et al. Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis. Nat Chem Biol. 2005 Jun;1(1):29-32.