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Menaquinone-7(Vitamin K2-7)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Menaquinone-7(Vitamin K2-7)图片
CAS NO:2124-57-4
规格:98%
分子量:649
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Menaquinone-7(VitaminK2-7)是维生素K2家族的成员,最早作为抗出血因子被发现。Menaquinone-7(VitaminK2-7)是Gla-蛋白羧化反应中最具生物活性的辅因子。补充Menaquinone-7(VitaminK2-7)也是激活Gla基质蛋白并干预钙化性主动脉瓣狭窄(CAVS)进展的一种药理选择。
CAS:2124-57-4
分子式:C46H64O2
分子量:649
纯度:98%
存储:Store at -20°C

Background:

Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].




[1]. Thijssen, H H., et al., 1994. Vitamin K distribution in rat tissues: dietary phylloquinone is a source of tissue menaquinone-4. The British journal of nutrition. 72(3): 415-25. [2]. Conly, J M., et al., 1994. The contribution of vitamin K2 (menaquinones) produced by the intestinal microflora to human nutritional requirements for vitamin K. The American journal of gastroenterology. 89(6): 915-23. [3]. Peeters FECM, et al. Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using 18F-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design. Nutrients. 2018 Mar 21;10(4). pii: E386.