您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > D-Glucosamine-2-sulfate(sodium salt)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
D-Glucosamine-2-sulfate(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
D-Glucosamine-2-sulfate(sodium salt)图片
CAS NO:38899-05-7
规格:98%
分子量:281.2
包装与价格:
包装价格(元)
1g电议
5g电议
10g电议

产品介绍
D-Glucosamine-2-sulfate (GlcN-2S), a sulfate derivative of glucosamine, is derived from chitin and has anti-inflammatory effects.
CAS:38899-05-7
分子式:C6H12NO8S.Na
分子量:281.2
纯度:98%
存储:Store at -20°C

Background:

D-Glucosamine-2-sulfate (GlcN-2S), a sulfate derivative of glucosamine, is derived from chitin and has anti-inflammatory effects. In vitro, it reduces expression of inflammatory markers, including IL-1β, COX-2, IL-6, and TNF-α in IL-1β-activated human chondrosarcoma SW1353 cells at a minimum effective concentration of 1 μM. At the same concentration, it limits expression of matrix metalloproteinase-3 (MMP-3) and a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5), both markers of matrix degradation. Treating human primary chondrocytes with GlcN-2S stimulates proteoglycan production at a dose of 10 μg/mL and adhesion to fibronectin at a concentration of 50 μM.