CAS NO: | 1504588-00-4 |
规格: | 98% |
分子量: | 389.9 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Background:
NAB 2 is an inhibitor of α-synuclein-induced toxicity. It prevents α-synuclein-induced defects in Rsp5-dependent endocytosis and vacuolar delivery of Mup1, Golgi-to-vacuole trafficking of Sna3, and degradation of Bap2 in wild-type yeast cells. NAB 2 also prevents formation of α-synuclein foci in wild-type yeast cells, an effect that is prevented by the rsp5G747E point mutation.