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Riluzole-13C,15N2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Riluzole-13C,15N2图片
CAS NO:1215552-03-6
包装:1mg
规格:98%
市场价:4068元
分子量:237.2

产品介绍
Riluzole-13C,15N2 is intended for use as an internal standard for the quantification of riluzole by GC- or LC-MS.
CAS:1215552-03-6
分子式:C7[13C]H5F3[15N]2OS
分子量:237.2
纯度:98%
存储:Store at -20°C

Background:

Riluzole-13C,15N2 is intended for use as an internal standard for the quantification of riluzole by GC- or LC-MS. Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Formulations containing riluzole have been explored as therapeutics for slowing disease progression of amyotrophic lateral sclerosis.