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diABZI STING agonist-1 Tautomerism
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
diABZI STING agonist-1 Tautomerism图片
CAS NO:2138498-18-5
规格:98%
分子量:849.94
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
diABZI STING agonist-1 (Tautomerism) 是一个选择性的干扰素基因刺激受体 (STING) 的激动剂,其在人中的 EC50 值为 130 nM。
CAS:2138498-18-5
分子式:C42H51N13O7
分子量:849.94
纯度:98%
存储:Store at -20°C

Background:

diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs. EC50: 130 nM (human STNG in PBMCs) [1].


diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.


diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. At a concentration of 1 μM, diABZI STING agonist-1 (compound 3) demonstrates high selectivity against more than 350 kinases tested[1].


[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.