HNMPA-(AM)3 is a cell-permeable prodrug form of the insulin receptor tyrosine kinase (IRTK) inhibitor HNMPA .
CAS:120944-03-8
分子式:C20H23O10P
分子量:454.4
纯度:98%
存储:Store at -20°C
Background:
HNMPA-(AM)3 is a cell-permeable prodrug form of the insulin receptor tyrosine kinase (IRTK) inhibitor HNMPA . HNMPA-(AM)3 inhibits IRTK autophosphorylation in CHO cells expressing the human receptor in a concentration- and time-dependent manner. It inhibits 2-deoxyglucose uptake but does not affect insulin-stimulated thymidine uptake in CHO cells at concentrations up to 100 μM.