Background:

Angiogenin (108-122) is an angiogenin peptide.

Angiogenin (108-122) effects on the ribonucleolytic activity of angiogenin using tRNA as substrate with 39% inhibition[1]. Angiogenin (108-122) acts as a therapeutic agent for the prophylaxis and/or treatment of cancer, an infectious disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, an autoimmune disease, or a heart and vascular disease[2].

[1]. Rybak SM, et al. C-terminal angiogenin peptides inhibit the biological and enzymatic activities of angiogenin. Biochem Biophys Res Commun. 1989 Jul 14;162(1):535-43. [2]. Dorian Bevec, et al. Therapeutic uses of angiogenin 108-122 and gluten exorphin a5. WO2009043455A2.