Hirsuteine 是一种从钩藤属植物中提取的吲哚生物碱。Hirsuteine 通过阻断离子渗透通过烟碱受体通道复合物，非竞争性地拮抗烟碱介导的多巴胺释放。
CAS：35467-43-7
分子式：C22H26N2O3
分子量：366.45
纯度：98%
存储：Store at -20°C

Background:

Hirsuteine is an indole alkaloid extracted from Uncaria genus. Hirsuteine non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes[1].

[1]. Watano T, et al. Non-competitive antagonism by hirsuteine of nicotinic receptor-mediated dopamine release from rat pheochromocytoma cells. Jpn J Pharmacol. 1993 Apr;61(4):351-6.