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N-[(4-Aminophenyl)methyl]adenosine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-[(4-Aminophenyl)methyl]adenosine图片
CAS NO:95523-13-0
规格:98%
分子量:372.38
包装与价格:
包装价格(元)
200mg电议
500mg电议
1mg电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
N-[(4-Aminophenyl)methyl]adenosine是腺苷受体抑制剂,作用于大鼠ecto-5′-Nucleotidase, Ki 值为29 nM。
CAS:95523-13-0
分子式:C17H20N6O4
分子量:372.38
纯度:98%
存储:Store at -20°C

Background:

N-[(4-Aminophenyl)methyl]adenosine is a adenosine receptor inhibitor, with Ki of 29 nM for Rat ecto-5′-Nucleotidase.IC50 value: 29.0 ± 1.7 nM (Ki) Target: Adenosine Receptor




[1]. Bhattarai S, et al. α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5’-Nucleotidase (CD73) Inhibitors. J Med Chem. 2015 Aug 13;58(15):6248-63. [2]. Chen JB, et al. Design and synthesis of novel dual-action compounds targeting the adenosine A(2A) receptor and adenosine transporter for neuroprotection. ChemMedChem. 2011 Aug 1;6(8):1390-400. [3]. Zhu Z, et al. Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity. Bioorg Med Chem. 2008 Apr 1;16(7):3848-65.