BTTAA是一种Cu(I)-稳定配体，能够很好地与泛素Glu18AzF反应。
CAS：1334179-85-9
分子式：C19H30N10O2
分子量：430.51
纯度：98%
存储：Store at -20°C

Background:

BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF.

BTTAA is a Cu(I)-stabilizing ligand. Using the Glu18AzF mutant of ubiquitin as a model system with C3-Tm3+ and C4-Tm3+, Cu-BTTAA performs significantly better as a catalyst than Cu-THPTA or Cu-TBTA. BTTAA proves to perform much better than THPTA (tris[(1-hydroxy-propyl-1H-1,2,3-triazol-4-yl)methyl]amine) or TBTA (tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine)[1].

[1]. Loh CT et al. Lanthanide tags for site-specific ligation to an unnatural amino acid and generation of pseudocontact shifts inproteins. Bioconjug Chem. 2013 Feb 20;24(2):260-8.