Phytic acid dodecasodium salt hydrate 是种子和谷粒的磷储存化合物。Phytic acid dodecasodium salt hydrate 被称为食品抑制剂，具有很强的螯合多价金属离子的能力，特别是锌，钙，铁和蛋白质残留物。Phytic acid dodecasodium salt hydrate 抑制超氧化物来源黄嘌呤氧化酶 (XO) 并具有抗氧化，神经保护以及抗炎作用。
CAS：123408-98-0
分子式：C6H18O24P6.XH2O.12Na
分子量：
纯度：98%
存储：Store at -20°C

Background:

Phytic acid dodecasodium salt hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium salt hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium salt hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects[1][2][3][4]. Xanthine oxidase[3]

Phytic acid dodecasodium salt hydrate (myo-Inositol) inhibits the formation of uric acid from xanthine with an IC50 of about 30 mM. The generation of the superoxide is greatly affected by Phytic acid dodecasodium salt hydrate; the IC50 is about 6 mM, indicating that the superoxide generating domain of XO is more sensitive to phytic acid[3].

[1]. Zhou JR, et al. Phytic acid in health and disease. Crit Rev Food Sci Nutr. 1995 Nov;35(6):495-508. [2]. Gupta RK, et al. Reduction of phytic acid and enhancement of bioavailable micronutrients in food grains. J Food Sci Technol. 2015 Feb;52(2):676-84. [3]. Muraoka S, et al. Inhibition of xanthine oxidase by phytic acid and its antioxidative action. Life Sci. 2004 Feb 13;74(13):1691-700. [4]. Lv Y, et al. Phytic acid attenuates inflammatory responses and the levels of NF-κB and p-ERK in MPTP-induced Parkinson’s disease model of mice. Neurosci Lett. 2015 Jun 15;597:132-6.