Guaijaverin 是一种尿素酶抑制剂，IC50 值为 120 μM。Guaijaverin 具有抗氧化和抗变形链球菌活性。
CAS：22255-13-6
分子式：C20H18O11
分子量：434.35
纯度：98%
存储：Store at -20°C

Background:

Guaijaverin is a urease inhibitor with an IC50 of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities[1][2][3]. IC50: 120 μM (Urease)[1]

Guaijaverin has anti-Strep.mutans activity, with MIC values of 4 and 2 mg/ml for MTCC 1943 and CLSM 001 strain of Strep. mutans, respectively[3].

[1]. Shabana S, et al. Inhibitory activity against urease of quercetin glycosides isolated from Allium cepa and Psidium guajava. Biosci Biotechnol Biochem. 2010;74(4):878-80. [2]. Caruso IP, et al. Exploring the binding mechanism of Guaijaverin to human serum albumin: fluorescencespectroscopy and computational approach. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Nov;97:449-55. [3]. Prabu GR, et al. Guaijaverin -- a plant flavonoid as potential antiplaque agent against Streptococcus mutans. J Appl Microbiol. 2006 Aug;101(2):487-95.