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Quetiapine sulfoxide dihydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Quetiapine sulfoxide dihydrochloride图片
CAS NO:329218-11-3
规格:98%
分子量:472.43
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) 是 Quetiapinem 的主要代谢产物。Quetiapinem 是第二代抗精神病药。
CAS:329218-11-3
分子式:C21H27Cl2N3O3S
分子量:472.43
纯度:98%
存储:Store at -20°C

Background:

Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic[1].



The Cmax value (mean±SD) is estimated for Quetiapine sulfoxide (77.3±32.4 ng/mL). The AUClast value is estimated for Quetiapine sulfoxide (1,286±458 ng•h/mL). For Quetiapine sulfoxide, metabolic ratio decreases with time, from 119% on average 2 hours after dosing to 30% on average 72 hours after dosing[1].


[1]. Remmerie B, et al. Comparison of Capillary and Venous Drug Concentrations After Administration of a Single Dose of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole. Clin Pharmacol Drug Dev. 2016 Nov;5(6):528-537.