CAS NO: | 382607-78-5 |
规格: | 98% |
分子量: | 616.53 |
包装 | 价格(元) |
100mg | 电议 |
200mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
Background:
Glucose-conjugated MGMT inhibitor is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells. MGMT|32 nM (IC50)
Glucose-conjugated MGMT inhibitor (O6BTG-octylglucoside) is a potent and non-toxic MGMT inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells[1].
[1]. Jost Reinhard, et al. Inactivation of O6-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors. Int.J.Cancer. (2001) 93,373-379.