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Glucose-conjugated MGMT inhibitor
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Glucose-conjugated MGMT inhibitor图片
CAS NO:382607-78-5
规格:98%
分子量:616.53
包装与价格:
包装价格(元)
100mg电议
200mg电议
5mg电议
10mg电议
50mg电议

产品介绍
Glucose-conjugated MGMT inhibitor 是一种有效的 MGMT 抑制剂,在细胞提取物及 HeLa S3 细胞中,IC50 值分别为 32 nM 和 10 nM。
CAS:382607-78-5
分子式:C24H34BrN5O7S
分子量:616.53
纯度:98%
存储:Store at -20°C

Background:

Glucose-conjugated MGMT inhibitor is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells. MGMT|32 nM (IC50)


Glucose-conjugated MGMT inhibitor (O6BTG-octylglucoside) is a potent and non-toxic MGMT inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells[1].



[1]. Jost Reinhard, et al. Inactivation of O6-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors. Int.J.Cancer. (2001) 93,373-379.