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Xanthopterin(hydrate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Xanthopterin(hydrate)图片
CAS NO:5979-01-1
规格:98%
分子量:197.15
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Xanthopterin hydrate,一种非共轭的蝶啶化合物,是东方大黄蜂翅膀中黄色颗粒的主要成分,在 386/456 nm 处产生特征性的激发光最大值。 Xanthopterin hydrate (XPT) 引起大鼠肾脏生长和肥大。Xanthopterin hydrate 抑制 RNA 合成。
CAS:5979-01-1
分子式:C6H7N5O3
分子量:197.15
纯度:98%
存储:Store at -20°C

Background:

Xanthopterin hydrate, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm[2]. Xanthopterin hydrate(XPT) causes renal growth and hypertrophy in rat[1].Xanthopterin hydrate inhibits RNA synthesis[4].


Xanthopterin (7.8-250 mM; 24 hours) show a significant reduction in mitochondrial activity with respect to controls (IC50=109 mM)[2]. Cell Viability Assay[2] Cell Line: MCF-7 cells



[1]. Xanthopterin (XPT), an unconjugated pteridine compound, affects cell growth and differentiation. When injected into rats, XPT has caused changes that have been interpreted as renal growth and hypertrophy. [2]. Lord JL, et al. Cytotoxicity of xanthopterin and isoxanthopterin in MCF-7 cells. Cancer Lett. 2005 May 10;222(1):119-24. [3]. Plotkin M, et al. Xanthopterin in the Oriental hornet (Vespa orientalis): light absorbance is increased with maturation of yellow pigment granules. Photochem Photobiol. 2009 Jul-Aug;85(4):955-61. [4]. Ziegler I, et al. Pterins and the regulation of lymphocyte activation on the mode of xanthopterin action. Hoppe Seylers Z Physiol Chem. 1984 Jun;365(6):667-73.