Filipin complex is a neutral polyene originally isolated from S.
CAS：11078-21-0
分子式：C35H58O11 (for Filipin III)
分子量：654.8
纯度：98%
存储：Store at -20°C

Background:

Filipin complex is a neutral polyene originally isolated from S. filipinensis with antifungal activity. It inhibits cell growth as well as mitochondrial terminal electron transport in S. cerevisiae when used at a concentration of 135 ug/ml. Filipin complex binds to various sterols, particularly 24α-methyl cholesterol 24α-ethyl cholesterol, and cholesterol, in aqueous solutions and in fungal cell membranes when used at a concentration of 50 ug/ml, inducing membrane pit formation and leakage of cell contents. It is a fluorescent compound that has been used to label sterols within biological structures for imaging. Filipin complex displays excitation/emission maxima of 338/480 nm, respectively.

参考文献:
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