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N-3-oxo-tetradec-7(Z)-enoyl-L-Homoserine lactone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-3-oxo-tetradec-7(Z)-enoyl-L-Homoserine lactone图片
CAS NO:482598-46-9
规格:98%
分子量:323.4
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.
CAS:482598-46-9
分子式:C18H29NO4
分子量:323.4
纯度:98%
存储:Store at -20°C

Background:

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases. AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. 3-oxo-C14:1-δ7cis-(L)-HSL is a bacterial quorum sensing compound that possesses antimicrobial activity, the ability to inhibit biofilm formation, and exhibits immune suppressive activity. This compound is structurally related to other 3-oxo-monounsaturated (N-acylated homoserine lactones) AHLs such as 3-oxo-C16:1-δ11cis-(L)-HSL (Catalog No. 10011238).