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C6 D-threo Ceramide(d18:1/6:0)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
C6 D-threo Ceramide(d18:1/6:0)图片
CAS NO:189894-79-9
包装:1mg
规格:98%
市场价:4286元
分子量:397.6

产品介绍
C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM).
CAS:189894-79-9
分子式:C24H47NO3
分子量:397.6
纯度:98%
存储:Store at -20°C

Background:

C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 μM but induces cell death at concentrations greater than 5 μM. It enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 μM.