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Reveromycin A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Reveromycin A图片
CAS NO:134615-37-5
规格:98%
分子量:660.8
包装与价格:
包装价格(元)
250ug电议
1mg电议

产品介绍
Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp.
CAS:134615-37-5
分子式:C36H52O11
分子量:660.8
纯度:98%
存储:Store at -20°C

Background:

Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 µg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 µg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 µg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in osteoclasts with an IC50 value of 0.7 µM.