CAS NO: | 287204-45-9 |
包装: | 10mg |
规格: | 98% |
市场价: | 3731元 |
分子量: | 429.27 |
Background:
ATP-competitive inhibitor of p210bcr/abl tyrosine kinase; selectively induces apoptosis in chronic myeloid leukemia (CML) K562 cells. Inhibits in vivo tyrosine phosphorylation of Gab2, CrkL and p210bcr/abl (IC50 values are 80, 80 and 170 nM respectively).