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CAY10580
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAY10580图片
CAS NO:64054-40-6
规格:98%
分子量:341.5
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议
10mg电议

产品介绍
Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4.
CAS:64054-40-6
分子式:C19H35NO4
分子量:341.5
纯度:98%
存储:Store at -20°C

Background:

Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10580 is an 8-aza-9-oxo-15-hydroxy saturated analog of PGE2. It selectively binds the EP4 receptor (Ki = 35 nM) relative to the EP1, EP2, and EP3 receptors (Ki = 3,000, 2,000, and >3,000 nM, respectively). CAY10580 stimulates cAMP formation in excised mouse ovaries.