MC-GGFG-DX8951, a DX8951 analog with antitumor activity, is a drug-linker conjugate used for synthesis of antibody drug conjugate (ADC) where DX8951 serves as a payload/warhead. It has a MC-GGFG linker, in which DX8951 was covalently connected via a peptidyl spacer (Gly-Gly-Phe-Gly), which is assumed to be stable in circulation, and were cleaved by lysosomal enzymes following ADC internalization into tumor tissue. MC-GGFG-DX8951 is very useful to prepare DX8951 antibody drug conjugate (ADC).

纯度：≥98%

CAS：1600418-29-8