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20-Hydroxyganoderic Acid G
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
20-Hydroxyganoderic Acid G图片
CAS NO:400604-12-8
规格:98%
分子量:548.66
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
20-Hydroxyganoderic Acid G 是从灵芝 (Ganoderma curtisii) 子实体的 EtOH 提取物中获得的羊毛甾烷三萜类化合物。20-Hydroxyganoderic Acid G 抑制由 LPS 激活的 BV-2 小胶质细胞,IC50 为 21.33 μM。20-Hydroxyganoderic Acid G 在治疗 LPS 激活的小胶质细胞相关的神经炎症疾病具有潜力。
CAS:400604-12-8
分子式:C30H44O9
分子量:548.66
纯度:98%
存储:Store at -20°C

Background:

20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia cells activated by LPS with an IC50 of 21.33 μM. 20-Hydroxyganoderic Acid G has therapeutic potential in the drug discovery of nerve inflammation diseases associated with microglia activated by LPS[1].




[1]. Jiao Y, et al. Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3556-61.