(S)-(+)-Quinuclidinol is a precursor in the synthesis of solifenacin.
CAS：34583-34-1
分子式：C7H13NO
分子量：127.2
纯度：98%
存储：Store at -20°C

Background:

(S)-(+)-Quinuclidinol is a precursor in the synthesis of solifenacin . Solifenacin is a competitive antagonist of muscarinic receptors that potently blocks signaling through M1, M2, and M3 (Kis = 25, 125, and 10 nM, respectively). Through this action, solifenacin prevents activation by acetylcholine, resulting in muscle relaxation. Formulations containing solifenacin have been used in the management of overactive bladder, as it reduces the number of micturition, urgency, and incontinence episodes.