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JJH260
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
JJH260图片
CAS NO:1831135-30-8
规格:98%
分子量:568.1
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs).
CAS:1831135-30-8
分子式:C29H34ClN5O5
分子量:568.1
纯度:98%
存储:Store at -20°C

Background:

JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). It blocks the hydrolysis of 9-PAHSA with an IC50 value of 0.57 µM. JJH260 also inhibits the novel FAHFA hydrolase androgen-dependent TFPI-regulating protein (ADTRP; IC50 = 8.5 µM), as well as the serine hydrolase ABHD6 and the lysophospholipases LYPLA1 and LYPLA2. JJH260 inhibits the FAHFA hydrolase activity of LNCaP and T cell lysates and intact cells.