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Salvinorin B Mesylate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Salvinorin B Mesylate图片
CAS NO:862073-79-8
规格:98%
分子量:468.5
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
Salvinorin B mesylate (Mesyl Sal B) is a selective κ-opioid receptor agonist that is more potent than salvinorin A in CHO cells transfected with the human κ-opioid receptor (EC50s = 30 and 40 nM, respectively).
CAS:862073-79-8
分子式:C22H28O9S
分子量:468.5
纯度:98%
存储:Store at -20°C

Background:

Salvinorin B mesylate (Mesyl Sal B) is a selective κ-opioid receptor agonist that is more potent than salvinorin A in CHO cells transfected with the human κ-opioid receptor (EC50s = 30 and 40 nM, respectively). It is a mesylated version of salvinorin B and is highly selective for κ-opioid receptors over µ- and δ-opioid receptors. In vitro, it increases dopamine uptake via the dopamine transporter (DAT) in an ERK1/2-dependent manner but does not alter expression of DAT on the cell membrane. In rats, it increases the pain threshold and blocks reinstatement of cocaine drug-seeking.