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Trientine(hydrochloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Trientine(hydrochloride)图片
CAS NO:38260-01-4
规格:98%
分子量:219.2
包装与价格:
包装价格(元)
250mg电议
500mg电议
1g电议

产品介绍
Trientine is a polyamine chelating agent.
CAS:38260-01-4
分子式:C6H18N4.2HCl
分子量:219.2
纯度:98%
存储:Store at -20°C

Background:

Trientine is a polyamine chelating agent. It reduces the amount of a copper-albumin complex and increases formation of low molecular weight complexes in a dialysis assay in a concentration-dependent manner. Trientine mobilizes copper ex vivo in human sera, increasing the supernatant percentage in an analytical ultracentrifugation experiment. In vivo, trientine (40 mg/kg, i.v.) mobilizes copper in the kidneys, but not the liver, to increase urinary excretion in rats. Trientine also decreases nickel accumulation in the liver, kidney, and spleen in mice injected with nickel chloride. Formulations containing trientine have been used to reduce copper accumulation in patients with Wilson’s disease.