Leptin(22-56),human是瘦蛋白(leptin)的多肽片段，通过Ob-Rs的多种亚型起作用。
CAS：183598-56-3
分子式：C171H298N50O56
分子量：3950.52
纯度：98%
存储：Store at -20°C

Background:

Leptin (22-56), human is the fragment of leptin, mediated via several isoforms of receptors (Ob-Rs).

Leptin (22-56), human is the fragment of leptin, inhibits corticosterone production, but shows no effect on the proliferation of cultured adrenocortical cells. Leptin (22-56) may be responsible for the direct inhibitory effect on secretion and growth of leptin on cultured rat adrenocortical cells[1]. Leptin (22-56) inhibits food intake, and may favour erythropoiesis[2].

[1]. Malendowicz LK, et al. Effects of leptin and leptin fragments on corticosterone secretion and growth of cultured rat adrenocortical cells. Int J Mol Med. 2004 Nov;14(5):873-7. [2]. Stamatiadis DN, et al. Elevated leptin fragments in renal failure correlate with BMI and haematopoiesis and are normalized by haemodialysis. Clin Endocrinol (Oxf). 2004 Apr;60(4):434-41.