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SA72
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SA72图片
CAS NO:934809-60-6
规格:98%
分子量:402.44
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
SA72是高度选择性的脂肪酸酰胺水解酶(FAAH)抑制剂。
CAS:934809-60-6
分子式:C21H26N2O6
分子量:402.44
纯度:98%
存储:Store at -20°C

Background:

SA72 is a highly selective fatty acid amide hydrolase (FAAH) inhibitor.


Fatty acid amide hydrolase (FAAH) is the primary regulator of several bioactive lipid amides including anandamide. Inhibitors of FAAH are potentially useful for the treatment of pain, anxiety, depression, and other nervous system disorders. However, FAAH inhibitors must display selectivity for this enzyme relative to the numerous other serine hydrolases present in the human proteome in order to be therapeutically acceptable. SA-72 is also a carbamate inhibitor. However, SA-72 shows exceptional selectivity for FAAH. Tested carboxylesterases are not off-targets for SA-72. SA-72 does not have major effects on the level of carboxylesterase activities in liver microsomes[1].



[1]. Zhang D, et al. Fatty acid amide hydrolase inhibitors display broad selectivity and inhibit multiple carboxylesterases as off-targets. Neuropharmacology. 2007 Mar;52(4):1095-105.