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CDD0102(CDD0102A)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CDD0102(CDD0102A)图片
CAS NO:146422-58-4
规格:98%
分子量:180.21
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
CDD0102是一种有效的M1毒蕈碱(Muscarinic)受体激动剂。
CAS:146422-58-4
分子式:C8H12N4O
分子量:180.21
纯度:98%
存储:Store at -20°C

Background:

CDD0102 is a potent M1 Muscarinic receptor agonist.


CDD0102 (CDD-0102) is an efficacious muscarinic agonist in cell lines expressing M1 receptors. CDD0102 displays much lower activity at M3 and M5 receptors[1].


After i.p. injections, CDD0102 (CDD-0102) crosses the blood-brain barrier (BBB) in a dose-dependent manner. In toxicological studies, the LD50 of CDD0102 is 190 mg/kg following i.p. injections and greater than 1,000 mg/kg following oral administration. In follow-up studies, after oral administration at a dose of 10 mg/kg, CDD0102 fully reverses memory deficits associated with IgG-192 saporin administration. Again, no side effects are observed at this dose[1].


[1]. Messer WS Jr. The utility of muscarinic agonists in the treatment of Alzheimer’s disease. J Mol Neurosci. 2002 Aug-Oct;19(1-2):187-93.