V-9302是一种跨膜谷氨酰胺通量的竞争性拮抗剂，能有效选择性的靶向氨基酸转运体ASCT2，其IC50值为9.6μM。V-9302显示抗肿瘤活性。
CAS：1855871-76-9
分子式：C34H38N2O4
分子量：538.68
纯度：98%
存储：Store at -20°C

Background:

V-9302 is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 with an IC50 of 9.6 μM. V-9302 exhibits anti-tumor activity[1]. IC50: 9.6 μM (ASCT2)[1]

[1]. Schulte ML, et al. Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacyin preclinical models. Nat Med. 2018 Feb;24(2):194-202.