| CAS NO: | 67247-12-5 |
| 包装: | 1mg |
| 规格: | 98% |
| 市场价: | 2223元 |
| 分子量: | 509.66 |
Background:
Boc-MLF (TFA) is a peptide, used as a specific formyl peptide receptor (FPR) antagonist, also inhibits the signaling through formyl peptide receptor like 1 (FPRL1) at higher concentrations[1].
Boc-MLF inhibits superoxide production induced by FPR agonist fMLF, with an EC50 of 630 nM in neutrophils[1].Boc-MLF (25 μM) blocks FPRL1-agonist serum amyloid A (SAA) induced calcium response[1].
参考文献:
[1]. Stenfeldt AL, et al. Cyclosporin H, Boc-MLF and Boc-FLFLF are antagonists that preferentially inhibit activity triggered through the formyl peptide receptor. Inflammation. 2007 Dec;30(6):224-9. Epub 2007 Aug 9.
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