Ramipril-d5 is intended for use as an internal standard for the quantification of ramipril by GC- or LC-MS.
CAS：1132661-86-9
分子式：C23H27D5N2O5
分子量：421.5
纯度：98%
存储：Store at -20°C

Background:

Ramipril-d5 is intended for use as an internal standard for the quantification of ramipril by GC- or LC-MS. Ramipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor ramiprilat . Ramipril (2.5 mg/kg per day, p.o.) reduces systolic blood pressure in spontaneously hypertensive rats. It reduces aortic valve backscatter and improves aortic flow in a rabbit model of aortic valve stenosis. Ramipril also decreases paw swelling and serum levels of TNF-α and prostaglandin E2 (PGE2) as well as cardiac collagen deposition and fibrosis in a rat model of adjuvant-induced arthritis.