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12(S)-HEPE
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
12(S)-HEPE图片
CAS NO:116180-17-7
规格:98%
分子量:318.5
包装与价格:
包装价格(元)
25ug电议
50ug电议
100ug电议

产品介绍
12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO.
CAS:116180-17-7
分子式:C20H30O3
分子量:318.5
纯度:98%
存储:Store at -20°C

Background:

12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.