CAS NO: | 115178-97-7 |
规格: | 98% |
分子量: | 390.4 |
包装 | 价格(元) |
25ug | 电议 |
50ug | 电议 |
100ug | 电议 |
Background:
20-trifluoro LTB4 is a synthetic analog of LTB4 resistant to metabolism by ω-oxidation. It is equipotent to LTB4 in chemotactic activity with an EC50 of 3 nM. In contrast to its chemotactic activity, 20-trifluoro LTB4 inhibits LTB4 induced degranulation of neutrophils with an IC50 of 1-2 nM.