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AR420626
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AR420626图片
CAS NO:1798310-55-0
规格:98%
分子量:417.3
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议
10mg电议

产品介绍
Free fatty acid receptor 3 (FFAR3; GPR41) is a G protein-coupled receptor activated by short chain fatty acids (SCFAs).
CAS:1798310-55-0
分子式:C21H18Cl2N2O3
分子量:417.3
纯度:98%
存储:Store at -20°C

Background:

Free fatty acid receptor 3 (FFAR3; GPR41) is a G protein-coupled receptor activated by short chain fatty acids (SCFAs). It is expressed in adipose tissue, the gastrointestinal tract, and the peripheral nervous system, and it is involved in SCFA-dependent energy regulation. AR420626 is a selective agonist of FFAR3 (GPR41; IC50 = 117 nM) that does not activate the related receptor FFAR2 (GPR43) at concentrations up to 100 µM. At 10 µM, it can stimulate a 1.26-fold increased release of glucagon-like peptide-1 from colonic crypt cultures.