CAS NO: | 359435-44-2 |
规格: | 98% |
分子量: | 770.9 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Background:
Glucose pentasulfate is a glucose derivative that contains five sulfate groups. It inhibits fibril formation by amyloid-β (1-40) (Aβ40) and induces dissolution of preformed Aβ40 fibrils in vitro in a concentration-dependent manner. Glucose pentasulfate inhibits Aβ interaction with heparan sulfate/heparin in a solid phase binding assay. It initially induces amylin fibrillogenesis but induces dissolution of preformed amylin containing fibrils by day 7 in a Thioflavin T fluorometry assay.