Background:

Pempidine is a ganglion-blocking drug, introduced as an oral treatment for hypertension.

[1]. Martin TJ, et al. Pharmacological evaluation of the antagonism of nicotine’s central effects by mecamylamine and pempidine. J Pharmacol Exp Ther. 1990 Jul;254(1):45-51. [2]. L. BRETHERICK, Congeners of Pempidine with High Ganglion-blocking Activity. Nature, 1959, 184: 1707-1709 )