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Argatroban monohydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Argatroban monohydrate图片
CAS NO:141396-28-3
规格:98%
分子量:526.65
包装与价格:
包装价格(元)
200mg电议
500mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Argatroban (monohydrate) (MD-805 (monohydrate)) 是 thrombin 选择性抑制剂。
CAS:141396-28-3
分子式:C23H38N6O6S
分子量:526.65
纯度:98%
存储:Store at -20°C

Background:

Argatroban (monohydrate) (MD-805 (monohydrate)) is a direct, selective thrombin inhibitor. Thrombin[1].


Argatroban (MD-805) may have a complementary effect for preventing thrombus formation without aggravating bleeding tendency because of its monotarget specificity to thrombin. Administration (0.5 to 2 micrograms/kg/min) of Argatroban (MD-805) is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries[1]. Argatroban (MD-805), as compared with heparin, appears to enhance reperfusion with TPA in patients with AMI, particularly in those patients with delayed presentation. The incidences of major bleeding and adverse clinical outcome were lower in the patients receiving argatroban[2].



[1]. Kawada, T., et al., Argatroban, an attractive anticoagulant, for left heart bypass with centrifugal pump for repair of traumatic aortic rupture. Jpn J Thorac Cardiovasc Surg, 1999. 47(3): p. 104-9. [2]. Jang, I.K., et al., A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. J Am Coll Cardiol, 1999. 33(7): p. 1879-85.