| CAS NO: | 169505-93-5 |
| 规格: | 98% |
| 分子量: | 449.42 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
Background:
RS 17053 hydrochloride is a novel and selective α1A-adrenoceptor antagonist [1].
α1A-adrenoceptor are widely distributed and activated either by epinephrine released from the adrenal medulla or by norepinephrine released from sympathetic nerve terminals. α1A-adrenoceptor mediate a variety of functions, including cardiac stimulation, contraction of smooth muscle, activation of hepatic gluconeogenesis， glycogenolysis, cellular proliferation and apoptosis.
In rat several tissues, RS-17053 had high affinity for the α1A -adrenoceptor and a 30
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