L888607Racemate是选择性前列腺素D2受体亚型1(DP1)的拮抗剂，其对DP1和TP的Ki值分别为132nM和17nM。
CAS：1030017-51-6
分子式：C19H15ClFNO2S
分子量：375.84
纯度：98%
存储：Store at -20°C

Background:

L 888607 Racemate is a selective prostaglandin D2 receptor subtype 1 (DP1) antagonist, with Kis of 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively.

L 888607 Racemate (compound 3) maintains a modest binding affinity for the DP1 receptor (Ki = 132 nM) and is actually 8-fold more potent on the TP receptor (Ki = 17 nM)[1].

[1]. Beaulieu C, et al. Identification of prostaglandin D2 receptor antagonists based on a tetrahydropyridoindole scaffold. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2696-700.