(Z)-Capsaicin 是 capsaicin 的顺式异构体，为可口服的 TRPV1 激动剂，可用于神经性疼痛的研究。
CAS：25775-90-0
分子式：C18H27NO3
分子量：305.41
纯度：98%
存储：Store at -20°C

Background:

(Z)-Capsaicin is the cis isomer of capsaicin, acts as an orally active TRPV1 agonist, and is used in the research of neuropathic pain. TRPV1 receptor[1]

(Z)-Capsaicin is the cis isomer of capsaicin, acting as a TRPV1 agonist. (Z)-Capsaicin may also blocks the neruonal calcium channel[1].

(Z)-Capsaicin (Zucapsaicin) significantly attenuates nociceptive behavior after oral administration in rats. (Z)-Capsaicin is also tolerated in the primary or recurrent experimental genital herpes simplex virus infection in guinea pigs[1].

[1]. Bourne N, et al. Civamide (cis-capsaicin) for treatment of primary or recurrent experimental genital herpes. Antimicrob Agents Chemother. 1999 Nov;43(11):2685-8.