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Teneligliptin hydrobromide hydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Teneligliptin hydrobromide hydrate图片
CAS NO:1572583-29-9
规格:98%
分子量:426.58
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
Teneligliptin hydrobromide hydrate 是一种有效的 DPP-4 抑制剂,竞争性抑制人血浆、大鼠血浆和重组人 DPP-4 的活性,IC50 值约为 1 nM。
CAS:1572583-29-9
分子式:C22H30N6OS
分子量:426.58
纯度:98%
存储:Store at -20°C

Background:

Teneligliptin hydrobromide hydrate is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM[1].




[1]. Fukuda-Tsuru S, et al. A novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, improves postprandial hyperglycemia and dyslipidemia after single and repeated administrations. Eur J Pharmacol. 2012 Dec 5;696(1-3):194-202.