INVIVO-0485, formerly known as KHK-IN-1, is a ketohexokinase (KHK) inhibitor. The last four digits of the compound's CAS registry number are used in its name. INVIVO-0485 interacts with Asp-27B in the ATP-binding region of KHK. INVIVO-0485 has potential for the treatment of diabetes and obesity. References: Maryanoff BE, O'Neill JC, McComsey DF, Yabut SC, Luci DK, Jordan AD Jr, Masucci JA, Jones WJ, Abad MC, Gibbs AC, Petrounia I. Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site. ACS Med Chem Lett. 2011 Apr 18;2(7):538-43. doi: 10.1021/ml200070g. eCollection 2011 Jul 14. Erratum in: ACS Med Chem Lett. 2012 Mar 8;3(3):263. PubMed PMID: 24900346; PubMed Central PMCID: PMC4018111.

纯度：≥98%

CAS：1303470-48-5