CAS NO: | 35299-94-6 |
规格: | 98% |
分子量: | 336 |
包装 | 价格(元) |
500ug | 电议 |
1mg | 电议 |
5mg | 电议 |
Background:
3-keto Sphinganine is an intermediate in the biosynthesis of C18 ceramide (d18:1/18:0) . It is a lyso-sphingolipid formed by the condensation of L-serine and palmitoyl-CoA by serine palmitoyl transferase (SPT). Vitamin K deficiency inactivates SPT resulting in a decrease in the production of 3-keto sphinganine and other sphingolipids.