Pyrogallol是一种多酚化合物，具有抗真菌和抗牛皮癣的特性。邻苯三酚是一种还原剂，能够产生自由基，特别是超氧阴离子。
CAS：87-66-1
分子式：C6H6O3
分子量：126.11
纯度：98%
存储：Store at -20°C

Background:

Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions.

Pyrogallol (PG) is a reductant that is able to generate free radicals, in particular superoxide anions (O2•-), so has frequently been used as a photographic developing agent and in the hair dying industry. Pyrogallol inhibits Calu-6 and A549 lung cancer cell growth via apoptosis and depletion of glutathione (GSH). Pyrogallol (PG) induces apoptosis in lung cancer cells via the overproduction of O2•- and affects mitogen activated protein kinases (MAPKs) in these cells[1]. The effect of Pyrogallol on human pulmonary fibroblast (HPF) cell viability and necrotic cell death is examined. For these experiments, 0, 50 or 100 µM Pyrogallol is used to differentiate the levels of cell viability inhibition or death with or without a given MAPK inhibitor. Treatment with 50 and 100 µM Pyrogallol decreases HPF viability by