Extracted?from?Pinus cerebra),cherry tree heartwood;Store?the?product?in?sealed,?cool?and?dry?condition
CAS：480-39-7
分子式：C15H12O4
分子量：256.25
纯度：98%
存储：Store at -20°C

Background:

Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties[1].

Pinocembrin (5, 10, 25, 50, 100 or 200 μM, 24 hours) significantly reduces cell viability of RBL-2H3 cells[1].Pinocembrin (25 or 50 μM) suppresses iNOS, PGE-2 and COX-2 levels, increases p38-Mapk and IкB-α, and inhibits phosphorylation of IкB-α[1].

参考文献:
[1]. Hanieh H, et al. Pinocembrin, a novel histidine decarboxylase inhibitor with anti-allergic potential in in vitro. Eur J Pharmacol. 2017 Nov 5;814:178-186.